For patients
Photo of a man and woman holding hands Photo of a man and woman holding hands

Actor portrayals.

Actor portrayals.

For the caregiver

Caregiving is an important part of the transplant experience

Being a caregiver means being a partner and offering ongoing support.

It’s important that you speak with the care team for any detailed instructions specific to the person you are caring for. The information provided here is a general overview and should not replace conversations with the care team about your role as a caregiver.

As the caregiver, you will:

  • Hospital iconStay with the person you are caring for at or near the treatment center for a number of weeks after the transplant. Check with your transplant team for specific requirements.
  • Cell iconKeep an eye out for side effects throughout recovery.
  • Caring hands iconHelp with daily activities such as getting dressed and eating.
  • Calendar iconHelp with scheduling and getting to and from appointments.

Actor portrayals.

Making sure the caregiver is also cared for

Being a caregiver is a full-time role. It can be demanding both physically and emotionally. So it’s important that you also take care of yourself.

Make sure you’re:

  • Getting enough sleep
  • Eating well-balanced meals
  • Taking breaks when you need to so you can reset and process all that is going on

Support for caregivers is available

There are many organizations dedicated to educating and supporting those living with cancer and their caregivers. You can find a list of resources here.

IMPORTANT SAFETY INFORMATION AND INDICATION

ISI tray

ISI tray

INDICATION

  • TREGZI is a treatment used in stem cell transplant for adult patients who have blood cancer to rebuild the blood and immune systems and improve survival without chronic graft-versus-host disease (cGVHD).
  • TREGZI is made by selecting certain types of blood cells from a matched donor.

IMPORTANT SAFETY INFORMATION

Before you receive TREGZI, tell your healthcare provider about all your medical conditions, including if you have:

  • Lung or breathing problems
  • Heart problems
  • Liver problems
  • Kidney problems
  • A recent or active infection

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

TREGZI can cause serious side effects, including:

  • Graft Failure. Failure to rebuild the blood and/or immune system, which may be fatal, can occur after receiving TREGZI. Your healthcare provider will monitor you closely after TREGZI administration.

  • Graft-Versus-Host Disease (GVHD). Immune reactions from the donor’s cells may occur soon (days) or long (months) after receiving TREGZI. Tell your healthcare provider right away about any signs and symptoms including rash, joint pain, diarrhea, or yellowing of the eyes.
  • Infusion Reactions. Infusion reactions can occur after TREGZI infusion. Tell your healthcare provider right away about any signs and symptoms including fever, chills, flushing, fatigue, shortness of breath, and dizziness/lightheadedness.
  • Secondary Cancer and Cancer from Donor Cells. New cancers can develop after treatment with TREGZI. If you are diagnosed with a new cancer after treatment, contact Orca Bio at 1-877-290-6722.
  • Transfer of Serious Infections. Transfer of serious infectious diseases can occur because TREGZI is made from the human blood cells of a donor. Transfer may occur even though donors are screened and tested for infectious diseases.

The most common side effects of TREGZI include inflammation of the digestive tract, diarrhea, rash, viral infections, infections from an unknown pathogen, abdominal pain, vomiting, nausea, bacterial infections, bleeding, acute graft-versus-host disease (aGVHD), swelling and fungal infections.

These are not all the possible side effects of TREGZI. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

INDICATION

  • TREGZI is a treatment used in stem cell transplant for adult patients who have blood cancer to rebuild the blood and immune systems and improve survival without chronic graft-versus-host disease (cGVHD).
  • TREGZI is made by selecting certain types of blood cells from a matched donor.

Please see accompanying full Prescribing Information including Patient Information.