For patients
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MyTREGZI support

myTREGZI support logo

Orca Bio is here to support you and your caregiver with access to TREGZI and for guidance throughout the treatment process.

You and your caregiver may receive help with*:

  • Transportation
  • Lodging
  • Out-of-pocket costs for meals 
  • Other travel expenses related to treatment with TREGZI 

MyTREGZI Support specialists can be reached by calling:

1-877-411-ORCA

(select option 4)

Monday through Friday,

8:00 AM to 8:00 PM Eastern Time

*Financial and other eligibility requirements apply.

Additional support resources

You are encouraged to speak with your care team as they are your best source of information. The following trusted, credible resources offer additional information you may find helpful.

Major national cancer organizations

American Cancer Society (ACS)

National Cancer Institute (NCI)

Blood Cancer United

MDS Foundation

MyLifeLine

Caregiver Action Network Care Chat

Blood and bone marrow transplant support organizations

National Marrow Donor Program (NMDP)

Blood & Marrow Transplant Information Network (BMT InfoNet)

Meredith A. Cowden Foundation

GVHD Alliance

Bone Marrow & Cancer Foundation

National Bone Marrow Transplant Link

The organizations listed here are independent from and not sponsored by Orca Bio, and this list is subject to change. This information is provided as a resource for patients and care partners, and is not an endorsement or guarantee of assistance.

Orca Bio has no financial interest in any organization listed, but may provide occasional funding support to these organizations.

IMPORTANT SAFETY INFORMATION AND INDICATION

ISI tray

ISI tray

INDICATION

  • TREGZI is a treatment used in stem cell transplant for adult patients who have blood cancer to rebuild the blood and immune systems and improve survival without chronic graft-versus-host disease (cGVHD).
  • TREGZI is made by selecting certain types of blood cells from a matched donor.

IMPORTANT SAFETY INFORMATION

Before you receive TREGZI, tell your healthcare provider about all your medical conditions, including if you have:

  • Lung or breathing problems
  • Heart problems
  • Liver problems
  • Kidney problems
  • A recent or active infection

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

TREGZI can cause serious side effects, including:

  • Graft Failure. Failure to rebuild the blood and/or immune system, which may be fatal, can occur after receiving TREGZI. Your healthcare provider will monitor you closely after TREGZI administration.

  • Graft-Versus-Host Disease (GVHD). Immune reactions from the donor’s cells may occur soon (days) or long (months) after receiving TREGZI. Tell your healthcare provider right away about any signs and symptoms including rash, joint pain, diarrhea, or yellowing of the eyes.
  • Infusion Reactions. Infusion reactions can occur after TREGZI infusion. Tell your healthcare provider right away about any signs and symptoms including fever, chills, flushing, fatigue, shortness of breath, and dizziness/lightheadedness.
  • Secondary Cancer and Cancer from Donor Cells. New cancers can develop after treatment with TREGZI. If you are diagnosed with a new cancer after treatment, contact Orca Bio at 1-877-290-6722.
  • Transfer of Serious Infections. Transfer of serious infectious diseases can occur because TREGZI is made from the human blood cells of a donor. Transfer may occur even though donors are screened and tested for infectious diseases.

The most common side effects of TREGZI include inflammation of the digestive tract, diarrhea, rash, viral infections, infections from an unknown pathogen, abdominal pain, vomiting, nausea, bacterial infections, bleeding, acute graft-versus-host disease (aGVHD), swelling and fungal infections.

These are not all the possible side effects of TREGZI. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

INDICATION

  • TREGZI is a treatment used in stem cell transplant for adult patients who have blood cancer to rebuild the blood and immune systems and improve survival without chronic graft-versus-host disease (cGVHD).
  • TREGZI is made by selecting certain types of blood cells from a matched donor.

Please see accompanying full Prescribing Information including Patient Information.